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CHAPTER SEVEN Learning ObjectivesAfter reading and studying this chapter the student should be able to
INTRODUCTIONHematopoiesis, the production of circulating erythrocytes, platelets and leukocytes from undifferentiated stem cells, is a remarkable process that produces over 200 billion new cells per day in the normal person and even greater number of blood cells in people with conditions that causes loss or destruction of blood cells. The hemopoietic machinery resides primarily in the bone marrow in adults, and requires constant supply of three essential nutrients – iron, vitamin B12 and folic acidANEMIA – a deficiency in oxygen carrying erythrocytes and very common in developing countriesIn this section anemia due to deficiency of iron, vit B12 or a folic acid will be dealt with.AGENTS USED IN ANEMIAS IRONIron forms the nucleus of the iron porphyrin heme ring, which together with globin chains forms hemoglobin that reversibly binds oxygen and provides the critical mechanism for oxygen
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