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INTRODUCTIONThe respiratory system includes the upper airway passages, the nasal cavities, pharynx and trachea as well as the bronchi and bronchioles. Respiration is the exchange of gases between the tissue of the body and to outside environment. It involves breathing in of an air through the respiratory tract, uptake of oxygen from the lungs, transport of oxygen through the body in the blood stream, utilization of oxygen in the metabolic activities (cells and removal of carbon dioxide from the body.
Drug therapy of pulmonary disorders is generally directed towards altering a specific physiologic function. The chapter will focus on drugs used to treat some of the more common disorders affecting the respiratory system particularly bronchial asthma, allergies and congestions associated with certain respiratory disorders..
Asthma is physiologically characterized by increased responsiveness of the trachea and bronchi to various stimuli and by wide spread narrowing of the airways that changes in severity either spontaneously or as a result of therapy.
Impairment of airflow in bronchial asthma is caused by three bronchial abnormalities.
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